The Global Fund to Fight AIDS, Tuberculosis and Malaria (Global Fund) is a multilateral financing mechanism that relies on public and private contributions on a three-year replenishment cycle. The Global Fund is a partnership between donor countries, the private sector and private foundations, implementing governments, civil society, international organizations, and affected communities. This partnership governs, oversees and implements the Global Fund’s strategic vision of ending HIV/AIDS, TB, and malaria while building resilient and sustainable systems for health, inherently strengthening country capacity to detect and respond to acute outbreaks and disease threats. Programs delivered with Global Fund dollars thereby also contribute to enhancing global health security and protecting America’s borders.

Since its inception in 2002, the United States has been a leader in financial and policy contributions to the Global Fund and is its largest single donor and technical resource for supporting program delivery at the country level. The United States is a permanent member of the Global Fund Board of Directors and currently has a formal role on each of the three Board sub-committees.

The U.S. investment in the Global Fund bolsters U.S. bilateral program results including that of PEPFAR, the President’s Malaria Initiative (PMI), and U.S. efforts to combat tuberculosis globally; expands the geographic reach of the U.S. global health response and investment; promotes sustainable country-owned responses to the three diseases, and attracts continued investments from other donors to the Global Fund. Since the beginning of our global response to the three diseases, it has been evident that no one country nor institution can accomplish the mission of controlling HIV, malaria, and TB alone. This can only be achieved through the complementary goals set by the leading institutions in the global health space, including PEPFAR, PMI, UNAIDS, the World Health Organization, Malaria No More, the Stop TB Partnership, and the Global Fund.

As a financing institution, the Global Fund’s operational model does not include an in-country presence. PEPFAR’s bilateral programming is a strong partner to the Global Fund, providing in-country intelligence and advice. The Global Fund Secretariat considers PEPFAR and the President’s Malaria Initiative as essential contributors to shaping the content of in-country grants. The same approach with the Secretariat is fostered in USAID TB programming.

The Global Fund held its 46th Board meeting virtually November 8-10, 2021. See the summary report [179 KB] for the meeting.

U.S. Department of State

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