Key Topics Office Home Key Topics HomeOffice of Commercial and Business Affairs...Key Topics hide Key Topics The State Department’s gateway for American businesses overseas Our mission is to employ U.S. government resources to assist and advocate for U.S. business interests abroad, encourage responsible business conduct, promote a vibrant ecosystem for entrepreneurship and innovation, and ensure U.S. private sector concerns are integrated into our foreign and economic policy. Discover More Commercial Diplomacy Read more Entrepreneurship Read more Responsible Business Conduct Read more Tools Deal Teams Direct Line for American Business Tools for Business Entrepreneurship Global Entrepreneurship Summits Conduct Responsible Business Conduct Fact Sheet Secretary of State’s Award for Corporate Excellence U.S. National Contact Point for the OECD Guidelines for Multinational Enterprises A Guide to the U.S. National Contact Point for the OECD Guidelines for Multinational Enterprises